A pandemia da COVID-19 não comprometeu o diagnóstico e o tratamento da malária em Mâncio Lima, no Acre, município brasileiro com maior incidência da doença. Leia na íntegra.
Autor: projetomina
Episódio 3: Coleta de material e atendimento médico: a dupla jornada de um pesquisador no Acre
No terceiro episódio da série Diário de Campo – Vale do Juruá, Marcelo Urbano Ferreira descreve protocolos utilizados no tratamento de pacientes com COVID-19 em Mâncio Lima, no oeste do Acre, e conta que, na ausência do médico, infectado com o SARS-CoV-2, ele próprio assumiu o atendimento dos doentes. Leia na íntegra.
Episódio 2: Análise genômica de material coletado de infectados ajudará a traçar rota do SARS-CoV-2 na região
No segundo episódio da série Diário de Campo – Vale do Juruá, Marcelo Urbano Ferreira e Marly Augusto Cardoso, pesquisadores do Instituto de Ciências Biomédicas (ICB) e da Faculdade de Saúde Pública (FSP) da Universidade de São Paulo (USP), respectivamente, descrevem, em vídeo e texto, os procedimentos de coleta de material para diagnóstico de infecção por SARS-CoV-2 e para a caracterização genômica do vírus na Unidade Básica de Saúde Raimundo Reginaldo, em Mâncio Lima, no Vale do Juruá, oeste do Acre. Leia na íntegra.
Episódio 1: Como a COVID-19 se disseminou no oeste do Acre
Marcelo Urbano Ferreira e Marly Augusto Cardoso, pesquisadores do Instituto de Ciências Biomédicas (ICB) e da Faculdade de Saúde Pública (FSP) da Universidade de São Paulo (USP), respectivamente, investigam, com apoio da FAPESP, a dinâmica de transmissão do SARS-CoV-2, que já matou 650 entre as cerca de 30 mil pessoas contaminadas no Acre. Leia na íntegra.
Agência FAPESP lança a série Diário de Campo no Vale do Juruá

A partir de segunda-feira (19/10) a Agência FAPESP publica a série Diário de Campo no Vale do Juruá, que descreve em cinco episódios a viagem de 10 dias feita no início de agosto pelos pesquisadores Marcelo Urbano Ferreira e Marly Augusto Cardoso – ambos da Universidade de São Paulo (USP) – à pequena cidade de Mâncio Lima, situada no Acre, perto da fronteira com o Peru. Leia na íntegra.
Publicações do Estudo MINA Brasil integram a coleção de saúde e nutrição materno infantil da revista internacional Plos One

Nos meses de julho e agosto, o Estudo MINA Brasil publicou três artigos científicos na Revista Internacional PLOS ONE, os artigos integram a coleção “Maternal and Child Health & Nutrition” e estão disponíveis gratuitamente no site da revista e na parte de publicações do site MINA. Leia mais aqui.
Agreement between antenatal gestational age by ultrasound and clinical records at birth: A prospective cohort in the Brazilian Amazon
This study aimed to assess agreement between antenatal estimates of gestational age by ultrasound and clinical records at birth in the Brazilian Amazon. Ultrasound examinations were scheduled during the second trimester for 578 pregnant women prospectively screened at primary health care units, following a standardized protocol for image quality control. A multistage algorithm was used to assess the best estimate of gestational age during the antenatal period, considering reliability of last menstrual period (LMP) and acceptable differences in relation to ultrasound estimates derived from fetal biparietal diameter and femur length. Agreement of antenatal estimates of gestational age confirmed by ultrasound and clinical records at birth was analyzed with Bland-Altman plots and kappa coefficients (preterm and postterm births). Overall, ultrasound examinations presented high quality (>90% of satisfactory images), and were adopted as the best estimate of gestational age among 83.4% of pregnant women, confirming reliable LMP in the remaining proportion. On average, difference in gestational age between antenatal estimates and clinical records was 0.43 week (95% CI: 0.32, 0.53). Classification of preterm births had a good agreement (kappa: 0.82, p<0.001), but a poor performance was observed for postterm births (kappa: -0.06, p = 0.92). Higher differences in gestational age were noted for participants with >11 years of education and cases of caesarean deliveries. In conclusion, high-quality ultrasound images from the second trimester of pregnancy based the assessment of gestational age, while reliability of LMP was limited. Information from clinical records at birth presented an acceptable agreement on average and for classification of preterm births, which is relevant for properly interpreting perinatal outcomes. Discrepancies in caesarean deliveries may warrant further investigation. Read the article.
Signs and strategies to deal with food insecurity and consumption of ultra-processed foods among Amazonian mothers
Although food insecurity configures a public health issue in developing countries going through nutrition transition, there is still lack of evidence on how it is affected by social determinants and its relationship with ultra-processed food (UPF) consumption. Using qualitative methods, we investigated the experience of food (in)security among mothers living in the Brazilian Amazon area, identifying aspects of food insecurity promoting UPF consumption. In-depth interviews were performed with 40 women and inductive content analysis was used. Signs of food insecurity included difficulties in food affordability and irregular access to food. Strategies to deal with lack of food quantity took place during food production (growing foods and raising animals), acquisition (gaining food, shopping incentives and food substitutions) and preparation (creativity in cooking). Not being able to afford staple foods was the main aspect of food insecurity promoting UPF consumption, as fresh foods were substituted by UFP options. Our study contributes to the current literature by presenting explanatory insights about the inconclusive quantitative results on the relationship between food insecurity and UPF consumption. Additionally, it supports the need of policies and interventions focused on promoting sustainable food systems and the regional food culture, which may approach food insecurity through an intersectional perspective. Read the article.
Cohort profile: the Maternal and Child Health and Nutrition in Acre, Brazil, birth cohort study (MINA-Brazil)
Maternal and Child Health and Nutrition in Acre, Brazil (MINA-Brazil) is a longitudinal, prospective population-based birth cohort, set-up to understand the effects of early environmental exposures and maternal lifestyle choices on growth and development of the Amazonian children. Mother–baby pairs (n=1246) were enrolled at delivery from July 2015 to June 2016 in Cruzeiro do Sul, Acre, Brazil. Mothers of 43.7% of the cohort were recruited in the study during pregnancy from February 2015 to January 2016. Study visits took place during pregnancy, delivery, at 1 month, 6 months, 1 year and 2 years after delivery. In addition to clinical and epidemiological data, samples collected by the MINA-Brazil study include plasma, serum and extracted DNA from blood and faeces, which are stored in a biobank. Key baseline reports found a high prevalence of gestational night blindness (11.5%; 95% CI 9.97% to 13.25%) and maternal anaemia (39.4%; 95% CI 36.84% to 41.95%) at delivery. Antenatal malaria episodes (74.6% of Plasmodium vivax) were diagnosed in 8.0% of the women and were associated with an average reduction in birth weight z-scores of 0.35 (95% CI 0.14 to 0.57) and in birth length z-scores of 0.31 (95% CI 0.08 to 0.54), compared with malaria-free pregnancies. At 2-year follow-up, data collection strategies combined telephone calls, WhatsApp, social media community and home visits to minimise losses of follow-up (retention rate of 79.5%). A 5-year follow-up visit is planned in 2021 with similar interviews and biospecimens collection. The findings from this prospective cohort will provide novel insights into the roles of prenatal and postnatal factors in determining early childhood development in an Amazonian population. Read the article.
Mothers’ food choices and consumption of ultra-processed foods in the Brazilian Amazon: A grounded theory study
In recent decades, an increase in consumption of ultra-processed foods (UPF), a type of product frequently associated with diet-related obesity, chronic diseases, decrease of eating traditions and loss of culinary diversity, has been observed in middle-income countries. However, there is lack of information on factors related to choosing UPF. In this study, we aimed to understand the factors promoting UPF choices and consumption among mothers living in an urban context in the Brazilian Amazon, and to present a conceptual model grounded on their experiences that illustrates the dynamics between the observed factors. For this qualitative study, we used a constructive grounded theory approach, with a theoretical sampling of 40 women, to choose mothers with high and low consumption of ultra-processed foods. Data production and the first steps of analysis were performed concomitantly, followed by four steps of coding focused on creating conceptual categories and explaining the interactions between them. Our findings highlighted the importance of context in promoting UPF choice and consumption, particularly the “food environment”, physical and virtual, and the “sociocultural environment”. These contextual aspects interacted with the two main personal aspects influencing participants’ UPF consumption, one concerning practices, “cooking behaviors”, and the other concerning preferences, “food tastes”. Factors such as economic and time constraints were also important and competed to shape eating practices through interactions with participants’ health valorization. Findings are discussed in relation to food choice theories, social roles and the food environment. Implications for public health initiatives include the importance of considering environmental changes, sociocultural and economic influences, the reliance on UPF, and the role of women in the home, when promoting healthy diets. Read the article.
